This function calculates the Quasi-Sequence-Order (QSO) descriptor with lag 12
QSOlevel(m)
m | A vector of k-mers |
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A matrix with the Quasi-Sequence-Order Descriptor (dim: 64)
QSO descriptor is calculated based on two physicochemical distance matrices: Schneider-Wrede (Schneider and Wrede, 1994) and Grantham physicochemical distance matrix (Grantham, 1974)
This is an internal function used inside predict_hyp
Kuo-Chen Chou. Prediction of Protein Subcellar Locations by Incorporating Quasi-Sequence-Order Effect. Biochemical and Biophysical Research Communications, 2000, 278, 477-483. Gisbert Schneider and Paul Wrede. The Rational Design of Amino Acid Sequences by Artifical Neural Networks and Simulated Molecular Evolution: Do Novo Design of an Idealized Leader Cleavage Site. Biophys Journal, 1994, 66, 335-344.
original R code by Nan Xiao, modified by Milan Dragićević